P1-245: CSF BIOMARKER CORRELATES OF ARTAG NEUROPATHOLOGY

CSF biochemical correlates of mixed affective states.

To evaluate the question of whether "mixed" bipolar disorder is a distinct entity, we compared selected cerebrospinal fluid (CSF) biochemical parameters from patients with bipolar disorder, mixed, to those with mania and major depression. Fourteen patients in each category (DSM-III) were studied with regard to CSF HVA, 5HIAA, sodium, potassium, calcium, and magnesium levels under carefully cont...

Progress in CSF biomarker discovery in sCJD

Sporadic Creutzfeldt-Jakob disease (sCJD) is the most prevalent form of human prion diseases caused by the misfolding of the cellular prion protein (PrPc) into its pathogenic form (PrPSc). It is clinically characterized by rapidly progressive dementia leading to the death of the patient usually in less than one year after disease onset. In the brain tissue, spongiform vacuolation, massive neuro...

Ijprbs 245

The study was done in 60 diabetic patients. These patients were divided into two groups, Group I (n=30) receiving Magnesium and Metformin therapy for a period of 16 weeks and Group II (n=30) receiving only Metformin therapy. The blood samples were collected and analyzed for Serum Magnesium and fasting blood glucose at 0, 4, 8, 16 weeks respectively. In GROUP I Mean Baseline value for S. Magnesi...

Dmd055400 245..249

Amlodipine is a commonly prescribed calcium channel blocker for the treatment of hypertension and ischemic heart disease. The drug is slowly cleared in humans primarily via dehydrogenation of its dihydropyridine moiety to a pyridine derivative (M9). Results from clinical drug-drug interaction studies suggest that CYP3A4/5 mediate metabolism of amlodipine. However, attempts to identify a role of...

Math 245 Notes: Syzygies